Using Mentzer Index to Improve Anemia Management in Pregnancy: A Narrative Review
DOI:
https://doi.org/10.22270/ajdhs.v5i1.106Keywords:
Mentzer Index, pregnancy, Anemia, Iron Deficiency, ThalassemiaAbstract
Anemia during pregnancy is a significant public health challenge, affecting maternal well-being and fetal development. Among the most common causes are iron deficiency anemia (IDA) and thalassemia trait (TT), conditions requiring distinct management strategies. Accurate differentiation between these conditions is critical, as misdiagnosis can lead to suboptimal treatment outcomes. The Mentzer Index, calculated by dividing the mean corpuscular volume (MCV) by the red blood cell (RBC) count, offers a simple and reliable tool for distinguishing between IDA and TT, especially in resource-limited settings. This review explores the utility of the Mentzer Index in improving anemia diagnosis and management in pregnancy. By analyzing routine complete blood count (CBC) results, the Mentzer Index allows for initial differentiation, facilitating timely and appropriate interventions. A Mentzer Index value of ≥13 indicates IDA, guiding clinicians toward iron supplementation, while a value <13 suggests TT, prompting further investigations and genetic counseling. This approach reduces unnecessary interventions, improves diagnostic accuracy, and ensures tailored management, mitigating complications such as preterm birth, low birth weight, and maternal morbidity.
Keywords: Mentzer Index, pregnancy, anemia, iron deficiency, thalassemia
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