Development and Evaluation of Aceclofenac Liposomes

Authors

  • Gurleen Kaur Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India https://orcid.org/0000-0001-7753-6880
  • Zaquiyya Naaz Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India
  • Kapil Kumar Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India https://orcid.org/0000-0003-0481-7109
  • Deepak Teotia Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

DOI:

https://doi.org/10.22270/ajdhs.v1i1.8

Keywords:

Dendrimers, Drug targeting, nanoscale carriers

Abstract

This review gives concise information about the application of dendrimers as drug delivery carrier in the field of drug delivery. Due to their unique architecture these have improved physical and chemical properties. Due to their terminal groups these show high solubility, miscibility and reactivity. Dendrimers have well defined size, shape, molecular weight and monodispersity. These properties make the dendrimers a suitable carrier in drug delivery application. Dendrimers are unimolecular miceller in nature and due to this enhances the solubility of poorly soluble drugs. Their compatibility with DNA, heparin and polyanions make them more versatile. Dendrimers, also referred as modern day polymers, they offer much more good properties than the conventional polymers. Due to their multivalent and mono disperse character dendrimers have stimulated wide interest in the field of chemistry biology, drug delivery, gene therapy and chemotherapy. Self-assembly produces a faster means of generating nanoscopic functional and structural systems. But their actual utility in drug delivery can be assessed only after deep understanding of factors affecting their properties and their behaviour in vivo.

Keywords: Dendrimers, Drug targeting, nanoscale carriers.

Author Biographies

Gurleen Kaur, Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

Zaquiyya Naaz, Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

Kapil Kumar, Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

Deepak Teotia, Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

Department of Pharmaceutics, Global Institute of Pharmaceutical Education and Research, Kashipur- 244713, Uttarakhand, India

References

Kong F, Zhou, Ge, Liu, Wang, Zhou. Mannosylated liposomes for targeted gene delivery. International Journal of Nanomedicine. 2012; 1079. https://doi.org/10.2147/IJN.S29183

Liu Q, Boyd BJ. Liposomes in biosensors. Analyst, 2012; in press. 2021.

Allison, Anthony C., and Gregory. Gregoriadis. Liposomes in Biological Systems. Chichester: John Wiley & Sons, Ltd., 1980. Print.

Deamer D. From "Banghasomes" to liposomes: A memoir of Alec Bangham, 1921-2010. The FASEB Journal. 2010; 24(5):1308-1310. https://doi.org/10.1096/fj.10-0503

Chioma E. Formulation and Evaluation of Etodolac Niosomes by Modified Ether Injection Technique. Universal Journal of Pharmaceutical Research. 2016; 1(1):1-6. https://doi.org/10.22270/ujpr.v1i1.R1

Anwar W, Dawaba HM, Afouna MI, Samy AM. Screening study forformulation variables in preparation and characterization of candesartan cilexetil loaded nanostructured lipid carriers. Universal Journal of Pharmaceutical Research 2019; 4(6):8-19. https://doi.org/10.22270/ujpr.v4i6.330

Singh B, Mehta G, Kumar R, Bhatia A, Ahuja N, Katare O. Design, Development and Optimization of Nimesulide-Loaded Liposomal Systems for Topical Application. Current Drug Delivery. 2005; 2(2):143-153. https://doi.org/10.2174/1567201053585985

Andhale A Varsha, Patil Priyanka R, Dhas Ahuja U, Chauhan Priyanka D, Desai Seema V, liposomes an emerging tool in drug carrier system. International journal of pharmacy and technology. 2016; 8(1): 10988- 11011.

Nwobodo NN, Adamude FA, Dingwoke EJ, Ubhenin A. Formulation and evaluation of elastic liposomes of decitabine prepared by rotary evaporation method. Universal Journal of Pharmaceutical Research 2019; 4(3):1-5. https://doi.org/10.22270/ujpr.v4i3.267

Dua J.S. et. al. Liposomes: Methods of preparation and application: International Journal of Pharmaceutical studies and research. 2012; 4:14-20.

Mishra H, Chauhan V, Kumar K, Teotia D. A comprehensive review on Liposomes: a novel drug delivery system. Journal of Drug Delivery and Therapeutics. 2018; 8(6):400-404. https://doi.org/10.22270/jddt.v8i6.2071

John DF, Yunus AA, Chigbo UJ, Paul US, Ikenna E. Tolnaftate loaded liposomes-design, and in-vitro evaluation. Universal Journal of Pharmaceutical Research 2016; 1(2): 29-31. https://doi.org/10.22270/ujpr.v1i2.R6

Subhash Chandran M.p, Prasbh G.R Jaghatha T, Aswathy B.S, Remya S.B. An overview on Liposomal drug delivery system. International Journal of Pharmaceutical and phytopharmcological research. 2019; 9(2):61-69.

Elsaied EH, Dawaba HM, Ibrahim ESA, Afouna MI. Effect of pegylated edge activator on Span 60 based nanovesicles: comparison between Myrj 52 and Myrj 59. Universal Journal of Pharmaceutical Research 2019; 4(4):1-8. https://doi.org/10.22270/ujpr.v4i4.290

Nagasany Venkatesh Dhandapani. Liposomes as Novel drug delivery system: A Comprehensive Review, Int J, Res. Pharm Sci, 4(2):187-193.

Kulkarni K, Priyanka R, Yadav JD, Vaidya KA. Liposomes a novel drug delivery system. International Journal of Current Pharmaceutical Research. 2011; 3(2):10-18.

Sharma A. Liposomes in drug delivery: Progress and limitations. International Journal of Pharmaceutics. 1997; 154(2):123-140. https://doi.org/10.1016/S0378-5173(97)00135-X

Shaheen SM, Ahmed FRS, Hossen MN, Ahmed M, Amran MS, Anwar-UL-Islam M, Liposome as a Carrier for Advanced Drug Delivery. Pakistan Journal of Biological Sciences. 2006; 9(6):1181-1191. https://doi.org/10.3923/pjbs.2006.1181.1191

Ugochukwu AE, Nnedimkpa OJ, Rita NO. Preparation and characterization of Tolterodine tartrate proniosomes. Universal Journal of Pharmaceutical Research 2017; 2(2):1-3. https://doi.org/10.22270/ujpr.v2i2.R1

Mishra H, Kaur G, Kumar K, Teotia D. Formulation and evaluation of liposomes of Indomethacin. Journal of advanced scientific research, 2019; 10(4):180-185.

Akbarzadeh A, Rezaei-Sadabady R, Davaran S, Joo S, Zarghami N, Hanifehpour Y et al. Liposome: classification, preparation, and applications. Nanoscale Research Letters. 2013; 8(1). https://doi.org/10.1186/1556-276X-8-102

Mathur P, Mathur CK, Mathur K. Oral drug delivery of insulin in diabetes mellitus: an attractive alternate to overcome invasive route. Universal Journal of Pharmaceutical Research 2018; 3(6): 45-48. https://doi.org/10.22270/ujpr.v3i6.221

Jadhav M, Gaikwad R, Kshirsagar N, Nagarsenker M, Samad A. Formulation and evaluation of long circulating liposomal Amphotericin B: A scinti-kinetic study using99mTc in BALB/C mice. Indian Journal of Pharmaceutical Sciences. 2011; 73(1):57. https://doi.org/10.4103/0250-474X.89757

Riaz Mohammad. Liposomes Preparation Methods. Pakistan Journal of Pharmaceutical Sciences.1991; 19(1):65-77.

Published

25.12.2021

How to Cite

Kaur, G. ., Naaz, Z. ., Kumar, K. ., & Teotia, D. . (2021). Development and Evaluation of Aceclofenac Liposomes . Asian Journal of Dental and Health Sciences, 1(1), 24–32. https://doi.org/10.22270/ajdhs.v1i1.8

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