Evaluation of Antioxidant Activity of Trigonella foenum graecum Seeds Extract

Authors

  • Neha Verma Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India
  • Vivekanand Katare Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India
  • Nisha Kalme Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India
  • Abhilasha Delouri Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India
  • Shivam Nema Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

DOI:

https://doi.org/10.22270/ajdhs.v3i1.33

Keywords:

Trigonella foenum graecum, Antioxidant, DPPH, Phytochemical analysis

Abstract

In the current work, we completed a comprehensive assessment of the relative antioxidant activity in extracts from a few different medicinal plant species.The extracts' effectiveness at scavenging 1, 1-diphenyl-2-picryl hydrazyl (DPPH) radicals was assessed spectrophotometrically. The highest degree of radical scavenging was 52.54%, while the IC50 value was 93.54.Trigonella foenum graecum extract demonstrates how the greater concentration of phytoconstituents chemicals leads to more powerful radical scavenging results.

Keywords: Trigonella foenum graecum, Antioxidant, DPPH, Phytochemical analysis

Author Biographies

Neha Verma, Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Vivekanand Katare, Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Nisha Kalme, Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Abhilasha Delouri, Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Shivam Nema, Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

Vivekanand College of Pharmacy, Shikandrabad, Bhopal, MP, 462044, India

References

Barlow SM. Toxicological aspects of antioxidants used as food additives. In Food Antioxidants, Hudson BJF (ed.) Elsevier, London, 1990; pp 253-307. https://doi.org/10.1007/978-94-009-0753-9_7

Branen AL. Toxicology and biochemistry of butylatedhydroxyanisol and butylatedhydroxytoluene. J. American Oil Chemists Society, 1975; 5:59- 63. https://doi.org/10.1007/BF02901825

Frankel E. Nutritional benefits of flavonoids. International conference on food factors: Chemistry and Cancer Prevention, Hamamatsu, Japan. Abstracts, 1995; C6- 2.

Gryglewski RJ, Korbut R, Robak J. On the mechanism of antithrombotic action of flavonoids. Biochemical Pharmacol, 1987; 36:317- 321. https://doi.org/10.1016/0006-2952(87)90288-7

Koleva II, Van Beek TA, Linssen JPH, De Groot A, Evstatieva LN. Screening of plant extracts for antioxidant activity: a comparative study on three testing methods. Phytochemical Analysis, 2002; 13:8-17. https://doi.org/10.1002/pca.611

Schuler P. Natural antioxidants exploited commercially, In Food Antioxidants, Hudson BJF (ed.). Elsevier, London, 1990; pp 99-170. https://doi.org/10.1007/978-94-009-0753-9_4

Mantle D, Eddeb F, Pickering AT. Comparison of relative antioxidant activities of British medicinal plant species in vitro, J. Ethnopharmacol. 2000; 72:47- 51. https://doi.org/10.1016/S0378-8741(00)00199-9

Merghem M, Dahamna S, In-Vitro Antioxidant Activity and Total Phenolic Content of Ruta montana L. Extracts, Journal of Drug Delivery and Therapeutics 2010; 10(2):69-75 https://doi.org/10.22270/jddt.v10i2.3919

Cook NC, Samman S. Flavonoids- chemistry, metabolism, cardioprotective effects, and dietary sources. Nutritional Biochemistry, 1996; 7:66-76. https://doi.org/10.1016/0955-2863(95)00168-9

Dutta R, Sharma MK, Khan A, Jha M. Phytochemical and in vitro antioxidant assay of Fumaria officinalis leaf extract. Journal of Advanced Scientific Research. 2020; 11(03):176-82.

Rani D, Kharkwal H, Jha M, Rai N. Assessment of the total flavonoid, phenol, alkaloid content and sun protection factor in Grewia abutilifolia leaf extract. Journal of Pharmaceutical Research International.2021; 33(49A):42-51. https://doi.org/10.9734/jpri/2021/v33i49A33300

Jha M, Ganesh N, Sharma V In vitro evaluation of free radical scavenging activity of Pistia stratiotes. International Journal of Chemtech Research 2010; 2(1):180-184

Jha M, Sharma V, Nema N, Hussain T. Effect of the topical application of the extract of Glycosmis pentaphylla on excisional wound model in mice. Pharmacologyonline. 2009; 3:356-60

Published

15.03.2023

How to Cite

Verma, N. ., Katare, V. ., Kalme, N. ., Delouri, A. ., & Nema, S. . (2023). Evaluation of Antioxidant Activity of Trigonella foenum graecum Seeds Extract. Asian Journal of Dental and Health Sciences, 3(1), 11–14. https://doi.org/10.22270/ajdhs.v3i1.33

Citations