Asian Journal of Dental and Health Sciences http://ajdhs.com/index.php/journal <p>Asian Journal of Dental and Health Sciences is a <em>double-blind peer-reviewed</em> <em>International </em>Journal dedicated to the publication of research papers, reviews, mini-reviews, Short communications and case studies. This publication is aimed at a broad, interdisciplinary audience of academic and industrial researchers actively engaged in basic and applied laboratory practice, related to dental &amp; health &amp; medical sciences.</p> Society of Pharmaceutical Tecnocrats en-US Asian Journal of Dental and Health Sciences 0000-0000 Dendrimers as Drug Delivery Carriers in the Dentistry http://ajdhs.com/index.php/journal/article/view/3 <p>This review gives concise information about the application of dendrimers as drug delivery carrier in the field of drug delivery. Due to their unique architecture these have improved physical and chemical properties. Due to their terminal groups these show high solubility, miscibility and reactivity. Dendrimers have well defined size, shape, molecular weight and monodispersity. These properties make the dendrimers a suitable carrier in drug delivery application. Dendrimers are unimolecular miceller in nature and due to this enhances the solubility of poorly soluble drugs. Their compatibility with DNA, heparin and polyanions make them more versatile. Dendrimers, also referred as modern day polymers, they offer much more good properties than the conventional polymers. Due to their multivalent and mono disperse character dendrimers have stimulated wide interest in the field of chemistry biology, drug delivery, gene therapy and chemotherapy. Self-assembly produces a faster means of generating nanoscopic functional and structural systems. But their actual utility in drug delivery can be assessed only after deep understanding of factors affecting their properties and their behaviour in vivo.</p> <p><strong>Keywords:</strong> Dendrimers, Drug targeting, nanoscale carriers.</p> Sunil Kumar Prajapati Vijay Kumar Tilak Ram Chand Dhakar Krishan Kumar Verma Vikrant Saluja R. Jayakumararaj Rajeshwar Kamal Kant Arya Manas Kumar Das Soumya Das Copyright (c) 2021 Sunil Kumar Prajapati, Vijay Kumar Tilak, R C Dhakar, Krishan Kumar Verma, Vikrant Saluja, R. Jayakumararaj, Rajeshwar Kamal Kant Arya, Manas Kumar Das, Soumya Das https://creativecommons.org/licenses/by-nc/4.0 2021-12-25 2021-12-25 1 1 1 9 10.22270/ajdhs.v1i1.3 Application of Moringa oleifera in Dentistry http://ajdhs.com/index.php/journal/article/view/5 <p>All part of the <em>Moringa tree is</em> useful in some way and people depends on it for their livelihood. Oral diseases persist to be a major health problem all over the world. Various microorganisms are found to be the possible pathogens responsible for the oral diseases. The leaves of the Moringa tree are an excellent source of Nutrients like Minerals, Protein and Vitamins (A and C). Moringa tree has approximately 46 antioxidants and it is one of the cheapest sources of natural anti-oxidants. Anti-oxidants supply the free atoms needed by the human body and mitigate the effect of free radicals. <em>M. oleifera</em> contains active compounds such as flavonoids, tannins, saponins, alkaloids, phenolics, and triterpenoids which possess antibacterial effects. <em>Moringa oleifera</em> has high mineral and protein content and has been previously investigated for its potential in treating different oral soft tissue diseases. Present review summarises the various application of <em>Moringa oleifera</em> in the field of dentistry.</p> <p><strong>Keywords:</strong><em> Moringa oleifera, </em>Anti-oxidants, Oral diseases, dentistry</p> Raghunandan Meena Sunil Kumar Prajapati Rajendra Nagar Omji Porwal Teena Nagar Vijay Kumar Tilak R. Jayakumararaj Rajeshwar Kamal Kant Arya Ram Chand Dhakar Copyright (c) 2021 Raghunandan Meena, Sunil Kumar Prajapati, Rajendra Nagar, Omji Porwal, Teena Nagar, Vijay Kumar Tilak, R. Jayakumararaj, Rajeshwar Kamal Kant Arya, Ram Chand Dhakar https://creativecommons.org/licenses/by-nc/4.0 2021-12-25 2021-12-25 1 1 10 13 10.22270/ajdhs.v1i1.5 A Review on Role of Herbal Antioxidants in Periodontitis http://ajdhs.com/index.php/journal/article/view/1 <p>Periodontal disease or Periodontitis is one of the common public health problems in the world and is most common reason of tooth loss in peoples. Periodontitis is highly prevalent and can affect up to 90% of the world population. Periodontitis is a gum infection that damages the soft tissues and bones present around tooth for support. Herbs and their extracts have long been used as a therapy for various diseases in the world due to their safety &amp; low cost. Currently herbal medicines are preferred due to their low cost, high safety margin and wider range of medicinal activities. Presence of excess free radicals results in oxidative damage of periodontal tissue. Herbal antioxidant reduces the deleterious action of free radicals and improves the oral health and decrease of inflammatory levels of periodontium. Thus, in this review we described the role of some herbal antioxidants as adjuvants for the management and treatment of Periodontitis.</p> <p><strong>Keywords:</strong> Periodontitis, herbal antioxidants, free radicals, periodontium</p> Sheo Datta Maurya Divya Jain Omji Porwal Ram Chand Dhakar R. Jayakumararaj Copyright (c) 2021 Divya Jain, Sheo Datta Maurya, Omji Porwal, Ram Chand Dhakar, R. Jayakumararaj https://creativecommons.org/licenses/by-nc/4.0 2021-12-25 2021-12-25 1 1 14 18 10.22270/ajdhs.v1i1.1 Antioxidant Potential of Cordia dichotoma: A Review http://ajdhs.com/index.php/journal/article/view/6 <p>Many plants of genus Cordia comprise of trees and shrubs are widely distributed in warmer regions and have been utilized in management of various diseases. Many phytochemicals like flavonoids, alkaloids, terpenes, tannins, and glyceridess having different activities were screened and isolated from different parts of <em>C. dichotoma</em>. Various important Pharmacological properties including Antiulcer, Contraceptives, anti-inflammatory, anthelmintic, analgesic, anticancer, Antioxidant, antimicrobial, hepatoprotective, antidiabetic and others have been well documented for this plant.<em> C. dichotoma is a</em> promising source of natural antioxidants which possess remarkable therapeutic action as inflammatory activity. In the present review, we have briefly reviewed the Antioxidant<em> Potential of </em><em>C. dichotoma</em> that can be followed for future research on this plant for health benefits.</p> <p>Keywords:<em> Cordia dichotoma</em>, Antioxidant, anti-inflammatory, flavonoids</p> Ram Chand Dhakar Sunil Kumar Prajapati Sheo Datta Maurya Vijay Kumar Tilak Manas Kumar Das Soumya Das Krishan Kumar Verma Nilesh Jain Copyright (c) 2021 Ram Chand Dhakar, Sunil Kumar Prajapati, Sheo Datta Maurya, Vijay Kumar Tilak, Manas Kumar Das, Soumya Das, Krishan Kumar Verma, Nilesh Jain https://creativecommons.org/licenses/by-nc/4.0 2021-12-25 2021-12-25 1 1 19 23 10.22270/ajdhs.v1i1.6 Development and Evaluation of Aceclofenac Liposomes http://ajdhs.com/index.php/journal/article/view/8 <p>This review gives concise information about the application of dendrimers as drug delivery carrier in the field of drug delivery. Due to their unique architecture these have improved physical and chemical properties. Due to their terminal groups these show high solubility, miscibility and reactivity. Dendrimers have well defined size, shape, molecular weight and monodispersity. These properties make the dendrimers a suitable carrier in drug delivery application. Dendrimers are unimolecular miceller in nature and due to this enhances the solubility of poorly soluble drugs. Their compatibility with DNA, heparin and polyanions make them more versatile. Dendrimers, also referred as modern day polymers, they offer much more good properties than the conventional polymers. Due to their multivalent and mono disperse character dendrimers have stimulated wide interest in the field of chemistry biology, drug delivery, gene therapy and chemotherapy. Self-assembly produces a faster means of generating nanoscopic functional and structural systems. But their actual utility in drug delivery can be assessed only after deep understanding of factors affecting their properties and their behaviour in vivo.</p> <p><strong>Keywords:</strong> Dendrimers, Drug targeting, nanoscale carriers.</p> Gurleen Kaur Zaquiyya Naaz Kapil Kumar Deepak Teotia Copyright (c) 2021 Gurleen Kaur, Zaquiyya Naaz, Kapil Kumar, Deepak Teotia https://creativecommons.org/licenses/by-nc/4.0 2021-12-25 2021-12-25 1 1 24 32 10.22270/ajdhs.v1i1.8