http://ajdhs.com/index.php/journal/issue/feed Asian Journal of Dental and Health Sciences 2022-05-15T16:24:47+00:00 Editor in Chief editor@ajdhs.com Open Journal Systems <p>Asian Journal of Dental and Health Sciences is a <em>double-blind peer-reviewed</em> <em>International </em>Journal dedicated to the publication of research papers, reviews, mini-reviews, Short communications and case studies. This publication is aimed at a broad, interdisciplinary audience of academic and industrial researchers actively engaged in basic and applied laboratory practice, related to dental &amp; health &amp; medical sciences.</p> http://ajdhs.com/index.php/journal/article/view/3 Dendrimers as Drug Delivery Carriers in the Dentistry 2022-05-02T18:11:58+00:00 Sunil Kumar Prajapati drsunilprajapati@gmail.com Vijay Kumar Tilak vijaykumartilak@gmail.com Ram Chand Dhakar dhakar_rc@yahoo.co.in Krishan Kumar Verma krrishver@gmail.com Vikrant Saluja saluja.vikrant@gmail.com R. Jayakumararaj jayakumar74@gmail.com Rajeshwar Kamal Kant Arya rajeshwararya@gmail.com Manas Kumar Das manas.kd@gmail.com Soumya Das saumya.mas@gmail.com <p>This review gives concise information about the application of dendrimers as drug delivery carrier in the field of drug delivery. Due to their unique architecture these have improved physical and chemical properties. Due to their terminal groups these show high solubility, miscibility and reactivity. Dendrimers have well defined size, shape, molecular weight and monodispersity. These properties make the dendrimers a suitable carrier in drug delivery application. Dendrimers are unimolecular miceller in nature and due to this enhances the solubility of poorly soluble drugs. Their compatibility with DNA, heparin and polyanions make them more versatile. Dendrimers, also referred as modern day polymers, they offer much more good properties than the conventional polymers. Due to their multivalent and mono disperse character dendrimers have stimulated wide interest in the field of chemistry biology, drug delivery, gene therapy and chemotherapy. Self-assembly produces a faster means of generating nanoscopic functional and structural systems. But their actual utility in drug delivery can be assessed only after deep understanding of factors affecting their properties and their behaviour in vivo.</p> <p><strong>Keywords:</strong> Dendrimers, Drug targeting, nanoscale carriers.</p> 2021-12-25T00:00:00+00:00 Copyright (c) 2021 Sunil Kumar Prajapati, Vijay Kumar Tilak, R C Dhakar, Krishan Kumar Verma, Vikrant Saluja, R. Jayakumararaj, Rajeshwar Kamal Kant Arya, Manas Kumar Das, Soumya Das http://ajdhs.com/index.php/journal/article/view/5 Application of Moringa oleifera in Dentistry 2022-05-10T12:55:37+00:00 Raghunandan Meena ram.c.dhakar@gmail.com Sunil Kumar Prajapati drsunilprajapati@gmail.com Rajendra Nagar ram.c.dhakar@gmail.com Omji Porwal omji.porwal@tiu.edu.iq Teena Nagar ram.c.dhakar@gmail.com Vijay Kumar Tilak vijaykumartilak@gmail.com R. Jayakumararaj jayakumar74@gmail.com Rajeshwar Kamal Kant Arya rajeshwararya@gmail.com Ram Chand Dhakar dhakar_rc@yahoo.co.in <p>All part of the <em>Moringa tree is</em> useful in some way and people depends on it for their livelihood. Oral diseases persist to be a major health problem all over the world. Various microorganisms are found to be the possible pathogens responsible for the oral diseases. The leaves of the Moringa tree are an excellent source of Nutrients like Minerals, Protein and Vitamins (A and C). Moringa tree has approximately 46 antioxidants and it is one of the cheapest sources of natural anti-oxidants. Anti-oxidants supply the free atoms needed by the human body and mitigate the effect of free radicals. <em>M. oleifera</em> contains active compounds such as flavonoids, tannins, saponins, alkaloids, phenolics, and triterpenoids which possess antibacterial effects. <em>Moringa oleifera</em> has high mineral and protein content and has been previously investigated for its potential in treating different oral soft tissue diseases. Present review summarises the various application of <em>Moringa oleifera</em> in the field of dentistry.</p> <p><strong>Keywords:</strong><em> Moringa oleifera, </em>Anti-oxidants, Oral diseases, dentistry</p> 2021-12-25T00:00:00+00:00 Copyright (c) 2021 Raghunandan Meena, Sunil Kumar Prajapati, Rajendra Nagar, Omji Porwal, Teena Nagar, Vijay Kumar Tilak, R. Jayakumararaj, Rajeshwar Kamal Kant Arya, Ram Chand Dhakar http://ajdhs.com/index.php/journal/article/view/1 A Review on Role of Herbal Antioxidants in Periodontitis 2022-04-13T13:54:36+00:00 Sheo Datta Maurya meetshiv23@gmail.com Divya Jain ram.c.dhakar@gmail.com Omji Porwal omporwal@gmail.com Ram Chand Dhakar dhakar_rc@yahoo.co.in R. Jayakumararaj jayakumar74@gmail.com <p>Periodontal disease or Periodontitis is one of the common public health problems in the world and is most common reason of tooth loss in peoples. Periodontitis is highly prevalent and can affect up to 90% of the world population. Periodontitis is a gum infection that damages the soft tissues and bones present around tooth for support. Herbs and their extracts have long been used as a therapy for various diseases in the world due to their safety &amp; low cost. Currently herbal medicines are preferred due to their low cost, high safety margin and wider range of medicinal activities. Presence of excess free radicals results in oxidative damage of periodontal tissue. Herbal antioxidant reduces the deleterious action of free radicals and improves the oral health and decrease of inflammatory levels of periodontium. Thus, in this review we described the role of some herbal antioxidants as adjuvants for the management and treatment of Periodontitis.</p> <p><strong>Keywords:</strong> Periodontitis, herbal antioxidants, free radicals, periodontium</p> 2021-12-25T00:00:00+00:00 Copyright (c) 2021 Divya Jain, Sheo Datta Maurya, Omji Porwal, Ram Chand Dhakar, R. Jayakumararaj http://ajdhs.com/index.php/journal/article/view/6 Antioxidant Potential of Cordia dichotoma: A Review 2022-05-10T13:23:56+00:00 Ram Chand Dhakar ram.c.dhakar@gmail.com Sunil Kumar Prajapati drsunilprajapati@gmail.com Sheo Datta Maurya meetshiv23@gmail.com Vijay Kumar Tilak vijaykumartilak@gmail.com Manas Kumar Das manas.kd@gmail.com Soumya Das manas.kd@gmail.com Krishan Kumar Verma krrishver@gmail.com Nilesh Jain prof.nileshjain@gmail.com <p>Many plants of genus Cordia comprise of trees and shrubs are widely distributed in warmer regions and have been utilized in management of various diseases. Many phytochemicals like flavonoids, alkaloids, terpenes, tannins, and glyceridess having different activities were screened and isolated from different parts of <em>C. dichotoma</em>. Various important Pharmacological properties including Antiulcer, Contraceptives, anti-inflammatory, anthelmintic, analgesic, anticancer, Antioxidant, antimicrobial, hepatoprotective, antidiabetic and others have been well documented for this plant.<em> C. dichotoma is a</em> promising source of natural antioxidants which possess remarkable therapeutic action as inflammatory activity. In the present review, we have briefly reviewed the Antioxidant<em> Potential of </em><em>C. dichotoma</em> that can be followed for future research on this plant for health benefits.</p> <p>Keywords:<em> Cordia dichotoma</em>, Antioxidant, anti-inflammatory, flavonoids</p> 2021-12-25T00:00:00+00:00 Copyright (c) 2021 Ram Chand Dhakar, Sunil Kumar Prajapati, Sheo Datta Maurya, Vijay Kumar Tilak, Manas Kumar Das, Soumya Das, Krishan Kumar Verma, Nilesh Jain http://ajdhs.com/index.php/journal/article/view/8 Development and Evaluation of Aceclofenac Liposomes 2022-05-15T16:24:47+00:00 Gurleen Kaur kapi5november@gmail.com Zaquiyya Naaz kapil5november@gmail.com Kapil Kumar kapil5november@gmail.com Deepak Teotia kapil5november@gmail.com <p>This review gives concise information about the application of dendrimers as drug delivery carrier in the field of drug delivery. Due to their unique architecture these have improved physical and chemical properties. Due to their terminal groups these show high solubility, miscibility and reactivity. Dendrimers have well defined size, shape, molecular weight and monodispersity. These properties make the dendrimers a suitable carrier in drug delivery application. Dendrimers are unimolecular miceller in nature and due to this enhances the solubility of poorly soluble drugs. Their compatibility with DNA, heparin and polyanions make them more versatile. Dendrimers, also referred as modern day polymers, they offer much more good properties than the conventional polymers. Due to their multivalent and mono disperse character dendrimers have stimulated wide interest in the field of chemistry biology, drug delivery, gene therapy and chemotherapy. Self-assembly produces a faster means of generating nanoscopic functional and structural systems. But their actual utility in drug delivery can be assessed only after deep understanding of factors affecting their properties and their behaviour in vivo.</p> <p><strong>Keywords:</strong> Dendrimers, Drug targeting, nanoscale carriers.</p> 2021-12-25T00:00:00+00:00 Copyright (c) 2021 Gurleen Kaur, Zaquiyya Naaz, Kapil Kumar, Deepak Teotia